Open Science Institute™ is a 501(c)3 project of the International Center for Integrative Systems. Open Science Institute™ provides the solution to address the existing inefficient research and development environment in the biological sciences that is being done in a medieval and corrupt framework. The collusion of Big Academia, Big Pharma, Big Foundations, Big Government has led to relatively minimal innovation and discoveries to advance human life. The Open Science Institute™ built by the people for the people, based on an engineering systems approach, delivers research and development faster, cheaper and better. These are the initiatives in which the public and donors can support, and witness how their support and contributions are leading to real results in a timely and tangible manner.